Our 2019 Research Annual Report
Post Date: February 4, 2020 | Publish Date:
- esophagus
- gastroenterology
- human genetics
- microbiome
- premier achievements
- preterm birth
- sickle cell disease
![Cover of Cincinnati Children's Research Annual Report](https://scienceblog.cincinnatichildrens.org/wp-content/uploads/2020/01/RAR2019_1000.jpg)
2019 Research Annual Report
“Spanning the full spectrum of discovery—basic exploration of biological mechanisms, translation to patients, and improvement of community health—our achievements in 2019 have surpassed all previous benchmarks.”
— Margaret K. Hostetter, MD
B.K. Rachford Professor
Chair, Department of Pediatrics; Director, Cincinnati Children’s Research Foundation; Chief Medical Officer
Read our 2019 Research Annual Report
![](https://scienceblog.cincinnatichildrens.org/wp-content/uploads/2020/01/20190919_Russell-Ware-and-Patrick-McGann_mw004-e1579267734411.jpg)
Daily Hydroxyurea Pill Safely Lowers Sickle Cell Burden Among African Children
Study published in the The New England Journal of Medicine
Results featured in the New York Times
![](https://scienceblog.cincinnatichildrens.org/wp-content/uploads/2020/01/20190919_Stephen-Trisno_mw011-e1579288564192.jpg)
First Human Esophagus Organoid Grown from Pluripotent Stem Cells
Study published in Cell Stem Cell
Learn more about our Center for Stem Cell & Organoid Medicine (CuSTOM)
![](https://scienceblog.cincinnatichildrens.org/wp-content/uploads/2020/01/schandower-RAR-4x3.jpg)
Probiotics Show No Benefit for Children with Acute Gastroenteritis
Study published in The New England Journal of Medicine
Learn more about Emergency Medicine research at Cincinnati Children’s
![](https://scienceblog.cincinnatichildrens.org/wp-content/uploads/2020/01/20190919_Lee-Denson_mw001-e1579289759652.jpg)
PROTECT Study Produces New Model for Treating Children with Ulcerative Colitis
Study published in The Lancet
Learn more about research at our Digestive Health Center
![](https://scienceblog.cincinnatichildrens.org/wp-content/uploads/2020/01/20190918_John-Hogenesch-and-Marc-Ruben_mw003-e1579290259901.jpg)
CYCLOPS Algorithm Helps Build Database of Cycling Genes in 13 Human Tissues
Study published in Science Translational Medicine
Read more about why Dosing Time Matters
![](https://scienceblog.cincinnatichildrens.org/wp-content/uploads/2020/01/20190924_Theresa-Alenghat_mw002-e1579291032698.jpg)
How the Gut Microbiome Influences Lean Vs. Obese Phenotypes
Study published in Gastroenterology
Read more about Dr. Alenghat’s microbiome research
![](https://scienceblog.cincinnatichildrens.org/wp-content/uploads/2020/01/Opthalmology_Lang-Nyugen-1-e1579291564746.jpg)