Research Horizons


COVID-19 Research News Update for April 7: American Heart Association Awards Project Funding

The Research Horizons science blog is sharing links to research-oriented news about the COVID-19 pandemic, especially information about how children are affected.

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From Cincinnati Children’s experts

View the first in a planned series of special Pediatric Grand Rounds presentations on COVID-19: The Basics

Presenters: Joshua Schaffzin, MD, and Felicia Scaggs Huang, MD

Cincinnati Children’s to join project funded by $14M grant from the American Heart Association

Cincinnati Children’s is one of four teams to form a “Strategically Focused Research Network” to respond to COVID-19, according to the AHA.

Among the details included in the funding announcement:

Active Detection and Decentralized Dynamic Registry to Improve Uptake of Rheumatic Heart Disease Secondary Prevention (ADD-RHD) at Cincinnati Children’s Hospital – Led by Andrea Beaton, MD, a pediatric cardiologist at Cincinnati Children’s Hospital, this team will address the global health issue of rheumatic heart disease which affects more than 40 million people, most living in poor countries or poor areas in wealthier countries. The team will concentrate on getting more people living with rheumatic heart disease into guideline-based care — using technology to find more people with rheumatic heart disease, keep them in care and generate the investment case to scale up national rheumatic heart disease action plans in low-income countries. Additionally, they’ll be looking for early career doctors and scientists who want to help people get better care using technology and educate this next generation in solutions developed to improve global health in the future. The team consists of a collaborative with the Rheumatic Heart Disease Research Collaborative in Uganda (RRCU) including the Uganda Heart Institute, Children’s National Medical Center and the University of Washington in Seattle; the Cincinnati Children’s Digital Experience and Bioinformatics Centers; Northern Kentucky University’s Biostatistics Department, Health Innovation Center and Health Sciences Institute; REACH (a global technical organization in rheumatic heart disease) and an industry partnership with Caption Health. While the project and solutions will be made for people living in developing countries, the team hopes to learn a lot about how to help people have better health in the United States.

Read the full announcement

More Research News
Children and COVID-19

MMWR: Cornonavirus Disease 2019 in Children — United States, February 12–April 2, 2020

COVIDview: A Weekly Surveillance Summary of U.S. COVID-19 Activity from the CDC

  • The overall cumulative COVID-19 associated hospitalization rate is 4.6 per 100,000, with the highest rates in persons 65 years and older (13.8 per 100,000) and 50-64 years (7.4 per 100,000).
  • NCHS is monitoring deaths associated with COVID-19 and made those data publicly available on April 3, 2020.

Science: A highly conserved cryptic epitope in the receptor-binding domains of SARS-CoV-2 and SARS-CoV

Lancet Public Health: Impact of school closures for COVID-19 on the US health-care workforce and net mortality: a modelling study

Clinical Infectious DiseasesMaternal and neonatal outcomes of pregnant women with COVID-19 pneumonia: a case-control study

American Journal of Obstetrics & Gynegology: COVID-19 infection among asymptomatic and symptomatic pregnant women: Two weeks of confirmed presentations to an affiliated pair of New York City hospitals

Journal of Pediatrics: Behavioral and Emotional Disorders in Children During the COVID-19 Epidemic

Healthcare Innovation: How Can Pediatric Health Systems Flex to Accommodate a Surge of Hospitalized Adults?

About POPCoRN: the Pediatric Overflow Planning Contingency Response Network. Co-founded by Leah Ratner, MD, MS, of Boston Children’s Hospital and Brigham and Women’s Hospital, and Ashley Jenkins, MD, of Cincinnati Children’s Hospital and University of Cincinnati Medical Center.

Science Translational Medicine: An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice

Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19)



NEW TO LIST: COVID-19 projections assuming full social distancing through May 2020

Pandemic tracker from Worldometer

Pandemic tracking dashboard from Johns Hopkins University

Ohio Department of Health: COVID-19 dashboard

Guidance for care providers from Cincinnati Children’s

A frequently updated collection of pediatric COVID-19 papers can be found here