Cincinnati Children’s Awarded 11 Grants from CancerFree KIDS
Post Date: December 11, 2024 | Publish Date:
CancerFree KIDS has continued its generous giving in the form of grants to 11 research projects at Cincinnati Children’s. The total amount awarded to research programs this round was $650,000.
With this year’s investments, the total grant funding to date from CancerFree KIDS to Cincinnati Children’s is over $6 million.
“CancerFree KIDS, over the last 20 years, have been extraordinarily successful in picking the right early projects, projects that otherwise would not get funded, and making that early investment is what allows it to work and grow,” says Stella Davies, MBBS, PhD, MRCP, director of Bone Marrow Transplantation and Immune Deficiency at Cincinnati Children’s. “So the success rate of CancerFree KIDS, in my opinion, is extraordinarily different than most organizations that fund research and that’s because they are clever in how they pick, and where they put their money – and so you, you are clever on where you pick and put your money, so thank you.”
The grants from the Loveland-based nonprofit range from $50,000 to $100,000 per project and will help fund studies of new AML therapies, CAR-T cell therapy, increased risk of hematological malignancy (HM) in sickle cell disease, and more.
“We are tremendously humbled by the generosity of our supporters at CancerFree KIDS,” said Jill Brinck, executive director of CancerFree KIDS. “Because of the record number of dollars raised, we will be able to fund important research to make the lives of our children better and give them hope for the future.”
The Cincinnati Children’s projects are:
New Idea Awards $50,000:
- Project Title: Targeting immune-checkpoint resistance in AML
- Principal Investigator: Mohammad Azam, PhD
- Project Title: Mechanisms underlying increased risk of hematological malignancy (HM) in sickle cell disease (SCD)
- Principal Investigator: Mengna Chi
- Project Title: Defining the role of DPF2 mutations in Acute Myeloid Leukemia
- Principal Investigator: Leighton Grimes, PhD
- Project Title: Developing therapies targeting Pro-Caspase-1 in pediatric AML
- Principal Investigator: Daniel Starczynowski, PhD (via Emma Uible BSc)
- Project Title: Harnessing stemness to improve CAR T cell efficacy in pediatric leukemia therapy
- Principal Investigator: Fukun Guo, PhD
- Project Title: To establish dMMR-deficient leukemic cell lines for use in FGS of small molecules target identification.
- Principal Investigator: Nicolas Nassar, PhD, Charles Dirr-Nims
- Project Title: T cell-directed drug repurposing to prevent progression of nervous system sarcoma
- Principal Investigator: Jay Pundavela, PhD
- Project Title: The use of LINE-1 as a novel biomarker and therapeutic target for pediatric cancers
- Principal Investigator: Kristie Ramos, MD
- Project Title: Targeting CDC42 reshapes glioblastoma immune microenvironment to benefit immunotherapy
- Principal Investigator: Yi Zheng, PhD
Accelerator Awards $100,000:
- Project Title: Targeting CAR-T cells Immune-resistance in B-ALL
- Principal Investigator: Mohammad Azam, PhD
- Project Title: Investigating recurrent PHIP mutations found in African ancestry Acute Myeloid Leukemia
- Principal Investigator: Bailee N. Kain, PhD
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