White Matter Measure Can Predict Brain Development Risk In Preterm Infants

Post Date: September 30, 2020


Lower row shows MRI scans using new software to detect volume of diffuse white matter abnormality (DWMA).

 “This advance will permit accurate parental counseling and early risk stratification to enable targeted early intervention therapies.”

–Nehal Parikh, DO, MS


Nehal Parikh, DO, MS

A new software tool developed at Cincinnati Children’s that quantifies white matter abnormalities can help predict which preterm infants are most at risk for developing cognitive, language, motor, or behavioral disorders.

Currently, many children facing brain development complications after early preterm birth are not diagnosed until they are 3 to 5 years old. This tool could allow earlier detection and intervention.

The tool’s latest milestone–predicting the risk of motor development disorders (e.g. cerebral palsy) –were detailed online Sept. 28, 2020, in Scientific Reports.

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The Research Horizons blog features news and insights about the latest discoveries and innovations developed by the scientists of Cincinnati Children's. This blog does not provide medical advice, diagnosis, or treatment.