Research Horizons


Takebe Receives NIH New Innovator Award

Organoid development expert Takanori Takebe, MD, is among 53 scientists nationwide to receive a “New Innovator” award from the National Institutes of Health High-Risk, High-Reward Research Program.

The award provides a five-year, $1.5 million grant to support Takebe’s Engineering Multi-Organs in a Dish project (Grant ID: DP2-DK128799)

Takebe is Director for Commercial Innovation at Cincinnati Children’s Center for Stem Cell and Organoid Research and Medicine (CuSTOM). He also holds an appointment as a professor at the Toyko Medical and Dental University’s Institute of Research in Japan.

Takebe, age 33, joined Cincinnati Children’s in 2016. His work includes multiple advances in liver organoid development, including recent success at building an organoid-based testing system to predict whether medications pose liver injury risk.

A year ago, Takebe and colleagues grew the world’s first interconnected three-organoid system, which included miniature versons of the liver, pancreas and bile ducts. Detailed findings appeared in the journal Nature.

“The breadth of innovative science put forth by the 2020 cohort of early career and seasoned investigators is impressive and inspiring,” said NIH Director Francis S. Collins, MD, PhD. “I am confident that their work will propel biomedical and behavioral research and lead to improvements in human health.”

Read more about organoid breakthroughs at Cincinnati Children’s

Read more about all the recipients of this year’s NIH high-risk, high-reward grants