Research Horizons


Our 2019 Research Annual Report

Cover of Cincinnati Children's Research Annual Report
2019 Research Annual Report

“Spanning the full spectrum of discovery—basic exploration of biological mechanisms, translation to patients, and improvement of community health—our achievements in 2019 have surpassed all previous benchmarks.”

Margaret K. Hostetter, MD

B.K. Rachford Professor
Chair, Department of Pediatrics; Director, Cincinnati Children’s Research Foundation; Chief Medical Officer


Read our 2019 Research Annual Report

Daily Hydroxyurea Pill Safely Lowers Sickle Cell Burden Among African Children

Study published in the The New England Journal of Medicine

Results featured in the New York Times


First Human Esophagus Organoid Grown from Pluripotent Stem Cells

Study published in Cell Stem Cell

Learn more about our Center for Stem Cell & Organoid Medicine (CuSTOM)

Probiotics Show No Benefit for Children with Acute Gastroenteritis

Study published in The New England Journal of Medicine

Learn more about Emergency Medicine research at Cincinnati Children’s

PROTECT Study Produces New Model for Treating Children with Ulcerative Colitis

Study published in The Lancet

Learn more about research at our Digestive Health Center


CYCLOPS Algorithm Helps Build Database of Cycling Genes in 13 Human Tissues

Study published in Science Translational Medicine

Read more about why Dosing Time Matters

How the Gut Microbiome Influences Lean Vs. Obese Phenotypes

Study published in Gastroenterology

Read more about Dr. Alenghat’s microbiome research

How Light Therapy Might Prevent Vision Problems in Preterm Infants

Study published in Nature Cell Biology

Read more about how other cell types outside the eye respond to light exposure