NIAMS-Funded Clinical Trial Featured on Lupus Foundation Podcast
Research By: Hermine Brunner, MD, MSc, MBA | Prasad Devarajan, MD
Post Date: February 9, 2024 | Publish Date:
Hermine Brunner, MD, MSc, MBA, professor and director of Cincinnati Children’s Division of Rheumatology, is featured in a recent episode of the Greater Ohio Chapter of the Lupus Foundation of America’s podcast, My Lupus Living Room.
In the episode, Brunner sheds light on a clinical trial she currently co-leads with Prasad Devarajan, MD, division director of Nephrology and Hypertension at Cincinnati Children’s, that focuses on personalized precision dosing of the immunosuppressive drug Mycophenolate Mofetil (MMF). Funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases, Brunner and Devarajan are conducting the Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study to look at two different methods for dosing MMF. The study would like to learn if one way is better at reaching the best possible levels of the drug MMF in the body.
Watch the podcast to learn more about their clinical trial.
I lead the Division of Rheumatology where we integrate clinical and translational research into daily care. My research work is made even more meaningful by interactions with the children and families I meet and serve in clinic, at our Lupus Center and within our lupus support groups.
Our research focuses on three areas: Investigating the mechanisms, biomarkers and novel therapies for acute kidney injury; studying the pathogenesis and biomarkers for focal segmental glomerulosclerosis; and identifying lupus nephritis molecular pathways and biomarkers.