Research Horizons


In Mice, a Common Antioxidant Boosts Biliary Atresia Survival

After identifying a 14-gene “signature” that predicts two year, transplant-free survival in children with biliary atresia, scientists here found that the antioxidant N-acetyl-cysteine (NAC) reduced liver injury and fibrosis and increased survival times.

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Publication Information
Original title: Gene Expression Signatures Associated With Survival Times of Pediatric Patients With Biliary Atresia Identify Potential Therapeutic Agents
Published in: Gastroenterology
Publish date: June 19, 2019
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Research By

Jorge Bezerra, MD
Director, Division of Gastroenterology, Hepatology and Nutrition