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50 Remarkable Discoveries and Accomplishments in 2024

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2024 Research Discoveries

Investigators from 50 research divisions at Cincinnati Children’s produced more than 3,400 peer-reviewed journal articles, book chapters, and other publications in FY2024. The following summaries represent the most significant findings, as selected by each division.

Adolescent and Transition Medicine

Trusted Clinicians Can Overcome Vaccine Hesitancy

Allergy and Immunology

Two Studies Changing the Field for Eosinophilic Esophagitis

Anesthesiology

Long-Lasting Pain Memory in Newborns

Asthma Research

Overactive Natural Killer Cells and Asthma Progression

Biomedical Informatics

New Tool Accelerates Hunt for Cancer Immunotherapy Targets

Biostatistics and Epidemiology

Developing a Framework for Studying Lung Function Decline in Cystic Fibrosis

Cancer & Blood Diseases Institute


Bone Marrow Transplant and Immune Deficiency
Vitamin A May Reduce CVHD Risk After Stem Cell Transplantation

Experimental Hematology and Cancer Biology
First Skeleton-Wide Study of Blood Cell Formation Yields Surprising Findings

Hematology
Prevalence and Predictors of HHT and CM-AVM in Children

Oncology
Improved Chemotherapy and Surgery Eliminating Need for Radiation for Low-Grade Gliomas

Critical Care Medicine

Community-Led Interventions to Address Food Inequity

Dermatology

Consensus Guidelines for Inpatient Management of EB

Developmental Biology

Pioneer Transcription Factors: Guardians of Cell Fate

Emergency Medicine

How to Identify Patients at High Risk for Cardiac Arrest with Intubation

Endocrinology

Continued Home Insulin Pump Use Proves Safe for Children in Hospitals

Every Child Succeeds

Maternal Depression May Affect Infant Epigenetic Aging

Gastroenterology, Hepatology, and Nutrition

Engineered Liver Organoids Offer New Hope for Severe Jaundice

General and Community Pediatrics

How COVID-19 Pandemic Impacted Kindergarten Readiness

Heart Institute


Cardiology
Mental Health in Children with Congenital Heart Disease

Cardiothoracic Surgery
Heart Surgeons Here Among Architects of New CHD Guidelines

Molecular Cardiovascular Biology
Breakthrough in Understanding Dilated Cardiomyopathy

Hospital Medicine

Can Behavioral Response Teams Reduce Staff Injuries?

Human Genetics

Utilization of Maternal Copper Concentration to Predict Preterm Birth Risk

Immunobiology

How the Microbiome Affects Type 2 Immunity

Infectious Diseases

How Moms ‘Remember’ Their Babies

James M. Anderson Center for Health Systems Excellence

How Health System Hesitancies Increased COVID-19 Risks

Mayerson Center for Safe and Healthy Children

Epigenetic Differences in Stress Response from Abusive vs Accidental Injuries

Mental and Behavioral Health Institute


Behavioral Medicine and Clinical Psychology
Early Behavioral Problems Linked to Family Stress

Child and Adolescent Psychiatry
Proactive Leadership to Address the Youth Mental Health Crisis

Developmental and Behavioral Pediatrics
Social Activities and Depression in Youth with ASD

Nephrology and Hypertension

New Paradigm for Kidney Fibrosis: Focus on the Distal Tubule

Neurology

Early Vigabatrin Treatment Prevents Infantile Spasms but Fails to Prevent Seizures Overall in Children with TSC

Neurosurgery

Stimulating V2a Neurons Improves Breathing in Mice After Spinal Cord Injury

Ophthalmology

Impact of Lighting on Rod Development in Preterm Mice

Orthopaedics

Zinc-Iron Alloy Shows Promise in Nerve Repair

Otolaryngology

Versatility of Slide Tracheoplasty

Pathology

Updated Classification of Pediatric Hepatic Vascular Tumors

Patient Services Research

Early Interventions Can Improve Hearing for Preterm Children

Pediatric & Adolescent Gynecology

Shared Algorithm Supports Ovary-Sparing Surgery

Pediatric Dentistry and Orthodontics

Cone Beam CT Wins the Race for Evaluating Alveolar Bone Grafts

Pediatric General and Thoracic Surgery

Two Possible Ways to Break Mother-to-Offspring Cycle of Fatty Liver Risk

Perinatal Institute


Neonatology and Pulmonary Biology
Single-Cell Atlas for ACDMPV Sheds New Light on Lung Development

Plastic Surgery

New Mouse Model May Shed Light on Alopecia Mechanisms

Pulmonary Medicine

Gene Editing Shows Promise for Correction of CFTR Variants Currently Without Treatment

Radiology

AI Model Outperforms Radiology Experts in Diagnosing Crohn’s Disease in Children

Rehabilitation Medicine

ROCS Tool Helps Confirm Optimal Care in Cerebral Palsy

Rheumatology

UDON Method Reveals Shared Gene Programs Across Inflammatory Diseases

Sports Medicine

Psychological Readiness May Outweigh Physical Readiness for Post-Surgery Return to Sport

Translational and Clinical Pharmacology

MTXPK.org Model Now Calibrated for Diverse Populations

Urology

Implementation of a Multidisciplinary Approach to Surgical Care in Pediatric Urology

 

Explore the 2024 Research Annual Report

 

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